Ketamine Providers in Indiana

10 providers across 4 cities

Indiana has 10 ketamine therapy providers across 4 cities. The most common provider types are ketamine infusion clinic, psychiatry practice, wellness & integrative center. Providers in Indiana commonly treat depression, anxiety, ptsd. Top cities include Indianapolis, Lafayette, Noblesville, Zionsville.

Ketamine Therapy in Indiana

Indiana combines some of the nation's most affordable ketamine infusion pricing with a clearly codified telehealth framework for controlled substance prescribing — making it one of the more accessible states for ketamine therapy in the Midwest. Indiana Medicaid updated its Spravato prior authorization criteria in early 2026, reflecting active state engagement with this treatment. Despite this, 222 additional mental health practitioners are still needed statewide.

Indiana ranks 24th nationally with 10 ketamine therapy providers, averaging 2.5 providers per city. The largest provider category is ketamine infusion clinic (40% of providers). Indianapolis leads the state with 6 providers.

State Regulations

Indiana classifies ketamine as a Schedule III controlled substance. Prescribers must hold DEA registration and check the Indiana INSPECT Prescription Drug Monitoring Program before issuing controlled substance prescriptions. Indiana does not enforce a rigid CPOM doctrine, permitting flexible clinic ownership. Indiana's telehealth law (IC 25-1-9.5) explicitly permits controlled substance prescribing via audiovisual telehealth consistent with DEA requirements.

Insurance & Medicaid Coverage

Indiana Medicaid (IHCP) covers Spravato with prior authorization, substantially updated effective October 1, 2025 (IHCP Bulletin BT202611, January 2026). Initial authorization requires TRD or MDD with acute suicidal ideation on concomitant oral antidepressant, age 18+, psychiatrist prescription, and REMS enrollment. For TRD: up to 8 kits per 4-week induction. Reauthorization requires 84 days of confirmed use plus clinical benefit.

Telehealth Options

Indiana law (IC 25-1-9.5) explicitly permits telehealth prescribing of controlled substances via audiovisual real-time communication without prior in-person examination when DEA requirements are met and INSPECT is queried. This is one of the more explicitly codified state telehealth frameworks for controlled substance prescribing.

Cost of Ketamine Therapy

IV ketamine infusions in Indiana typically cost $325–$500 per session. Indiana offers some of the most competitive ketamine pricing nationally. Evansville Ketamine lists a 6-session series for $1,950. Complete Ketamine Solutions (Indianapolis) prices a 6-session mood series at $2,400. A standard initial series of 6 infusions runs $1950–$2800. Spravato (esketamine) may be partially or fully covered by insurance.

Mental Health Access

Indiana has 39.89% of mental health needs met as of December 2025 (HRSA data), with 222 additional practitioners needed — one of the largest absolute gaps in the Midwest. Rural Indiana counties, particularly in the south and east, carry the highest HPSA burden. Indiana has approximately 0.16 ketamine providers per 100,000 residents.

Frequently Asked Questions

Is ketamine therapy legal in Indiana?

Yes. Ketamine is a Schedule III controlled substance that may be legally prescribed and administered by DEA-registered providers for off-label uses including treatment-resistant depression, PTSD, and chronic pain. Indiana does not enforce a strict CPOM doctrine. All prescribers must check Indiana's INSPECT Prescription Drug Monitoring Program.

Does Indiana Medicaid cover Spravato?

Yes. Indiana Medicaid (IHCP) covers Spravato with prior authorization, updated most recently in January 2026. Initial authorization requires a diagnosis of TRD or MDD with acute suicidal ideation, age 18+, psychiatrist oversight, and REMS enrollment. Reauthorization requires 84 days of prior use confirmed by claim history.

How much does ketamine infusion therapy cost in Indiana?

Indiana offers some of the most affordable ketamine infusion pricing in the country. Evansville Ketamine prices a 6-session series at $1,950 (approximately $325/session). Complete Ketamine Solutions in Indianapolis prices a 6-session mood series at $2,400. Veterans often receive a 10% discount at multiple Indiana clinics.