Ketamine Providers in Ohio

14 providers across 9 cities

Ohio has 14 ketamine therapy providers across 9 cities. The most common provider types are ketamine infusion clinic, mental health practice, med spa & aesthetic. Providers in Ohio commonly treat depression, anxiety, ptsd. Top cities include Dayton, Dublin, Gahanna, Willoughby, Cincinnati.

Ketamine Therapy in Ohio

Ohio is home to a growing network of ketamine therapy clinics serving patients with treatment-resistant depression, PTSD, anxiety, chronic pain, and related conditions. Anchored by Ohio State University Wexner Medical Center's interventional psychiatry program — one of the earliest and most research-active programs in the Midwest — the state offers access to both IV ketamine and FDA-approved Spravato. With 75 of 88 counties designated as mental health professional shortage areas, ketamine therapy fills a critical gap in psychiatric care for Ohioans.

Ohio ranks 20th nationally with 14 ketamine therapy providers, averaging 1.6 providers per city. The largest provider category is ketamine infusion clinic (78.6% of providers). Dayton leads the state with 3 providers.

State Regulations

Ohio follows federal Schedule III guidelines for ketamine with no state-specific ketamine clinic legislation. The Ohio State Medical Board oversees prescribers under standard controlled substance rules. Clinics need no separate state registration, but practitioners must hold active DEA registration for each treatment location. Ohio is a non-CPOM state, allowing flexible clinic ownership structures.

Insurance & Medicaid Coverage

Ohio Medicaid (via CareSource/UHC Community Plan) covers Spravato with prior authorization. Requirements include age 18+, TRD or MDD with acute suicidal ideation, failure of two antidepressants from different classes at optimized doses for at least 8 weeks, and psychiatrist prescription at a REMS-certified center. As of February 2025, TRD indication no longer requires concurrent oral antidepressant. Initial approval is 2 months.

Telehealth Options

Under the DEA's extension through December 31, 2026, Ohio practitioners may prescribe ketamine via telemedicine without a prior in-person evaluation. Ohio has no additional state restrictions beyond federal telehealth rules.

Cost of Ketamine Therapy

IV ketamine infusions in Ohio typically cost $400–$750 per session. Columbus and Cleveland clinics typically price IV infusions in the $400-$600 range. Multi-location providers and Ohio State Wexner (primarily Spravato) represent the major market anchors. A standard initial series of 6 infusions runs $2400–$4500. Spravato (esketamine) may be partially or fully covered by insurance.

Mental Health Access

Ohio has 33.73% of mental health needs met, requiring 247 additional practitioners to remove HPSA designations (HRSA, December 2025). As of July 2025, 75 of Ohio's 88 counties were designated as mental health professional shortage areas. Ohio has approximately 0.19 ketamine providers per 100,000 residents.

Frequently Asked Questions

Is ketamine therapy legal in Ohio?
Yes. Ketamine is a Schedule III controlled substance legal for off-label therapeutic use in Ohio when administered by a licensed provider with valid DEA registration. Ohio imposes no additional clinic registration requirements beyond standard DEA and state medical board licensing.
Does Ohio Medicaid cover ketamine therapy?
Ohio Medicaid does not cover IV ketamine infusions (off-label, self-pay at $400-$750 per session). However, Ohio Medicaid managed care plans do cover Spravato (esketamine nasal spray) for qualifying patients with TRD or MDD with suicidal ideation, with prior authorization and psychiatrist prescription at a REMS-certified center.
How much does ketamine therapy cost in Ohio?
IV ketamine infusions in Ohio typically run $400-$750 per session, with a standard 6-session series costing approximately $2,400-$4,500. Some clinics offer package pricing. Spravato costs vary widely based on insurance status — insured patients may pay as little as $10-$50 per session in copays.

Learn More About Ketamine Therapy

Cities with 3+ Providers

Cincinnati, OH (1)

Columbus, OH (1)

Dayton, OH (3)

Dublin, OH (2)

Ketamine Health & Wellness Clinics of Ohio
Dublin, OH · Ketamine Infusion Clinic
Ketamine Health & Wellness Clinics of Ohio is the foremost provider of psychiatric care and ketamine therapy in the Greater Columbus area. Based in Dublin, Ohio, the practice is the only Columbus-area ketamine clinic with a psychiatrist on staff. The team of skilled providers truly understands the challenges their patients have coping with anxiety, depression, suicidal ideation, obsessive-compulsive disorder (OCD), post-traumatic stress disorder (PTSD), and other psychiatric conditions. They provide compassionate care and are deeply invested in relieving each patient's distress by offering groundbreaking treatments like ketamine and Spravato®, along with psychiatric medication management. The Ketamine Health & Wellness Clinics of Ohio team provides comprehensive mental health care, and they're dedicated to excellent patient experiences and results. They go the extra mile to ensure patient safety, using ultrasound-led infusions, blood pressure finger readings, and consistent noninvasive monitoring throughout every treatment. Ketamine has shown remarkable results for patients with mental health challenges, and the Ketamine Health & Wellness Clinics of Ohio team wants to make this remarkable treatment option available for all. Call the office or book an appointment online today.
Ketamine Infusion Clinic Depression Anxiety Ptsd
Zylem Ketamine Wellness
Dublin, OH · Ketamine Infusion Clinic
Zylem Ketamine Wellness uniquely blends ketamine therapy with personalized integrative coaching. Under Dr. Anthony Tran and Peter Tran, we prioritize a transformative approach, focusing on both symptom relief and personal development. Our clinic excels in providing holistic care. The journey begins with three focused coaching calls to set clear goals and prepare mentally for the ketamine experience. Our six 90-minute ketamine therapy sessions are designed not just as medical procedures but as steps in a profound journey of healing and self-exploration. These are complemented by integration coaching calls, ensuring experiences are meaningfully processed. Our commitment and partnership with you extends beyond immediate treatment. We engage in follow-ups at four weeks and four months, demonstrating our dedication to our clients' long-term wellness. Zylem Ketamine Wellness isn't just about treating mental health issues; it's about empowering individuals towards a more fulfilled, self-aware life. Our combination of medical expertise and personal coaching, offered in a supportive environment, makes us a distinctive choice in psychedelic therapy and personal development. We are partners in our clients' journeys to a brighter self.
Ketamine Infusion Clinic Depression Anxiety Ptsd

Gahanna, OH (2)

Lakewood, OH (1)

Oberlin, OH (1)

Toledo, OH (1)

Willoughby, OH (2)