Ketamine Providers in Maine
3 providers across 3 cities
Maine has 3 ketamine therapy providers across 3 cities. The most common provider types are psychiatry practice, wellness & integrative center. Providers in Maine commonly treat depression, anxiety, chronic pain. Top cities include Camden, Falmouth, Portland.
Ketamine Therapy in Maine
Maine patients struggling with treatment-resistant depression, PTSD, anxiety, and chronic pain increasingly have access to ketamine therapy — primarily through clinics concentrated in Portland and southern Maine. With the state's rural geography and persistent mental health provider shortages across northern counties, telehealth-enabled ketamine evaluations are an important pathway for patients far from urban centers.
Maine ranks 38th nationally with 3 ketamine therapy providers, averaging 1 provider per city. The largest provider category is psychiatry practice (66.7% of providers). Camden leads the state with 1 provider.
State Regulations
Maine regulates ketamine under its joint controlled substance prescribing rule (Chapter 21) issued by the Board of Licensure in Medicine, State Board of Nursing, Board of Osteopathic Licensure, and Board of Licensure of Podiatric Medicine. Maine does not enforce a formal CPOM doctrine, allowing more flexible clinic ownership. Providers must use electronic prescribing for controlled substances and check the Maine PMP.
Insurance & Medicaid Coverage
MaineCare (Maine's Medicaid program) covers Spravato for qualifying members with prior authorization. Coverage applies to adults 18+ with treatment-resistant depression who have failed at least two adequate antidepressant trials, prescribed by or in consultation with a psychiatrist, at a REMS-certified facility with mandatory 2-hour post-dose monitoring. IV ketamine is not covered.
Telehealth Options
Under the DEA's extension through December 31, 2026, Maine providers may prescribe ketamine via telehealth without a prior in-person visit. Maine's rural geography — with many residents more than 30 minutes from a mental health provider — makes telehealth especially important for ketamine evaluations and follow-up care.
Cost of Ketamine Therapy
IV ketamine infusions in Maine typically cost $400–$800 per session. Portland Ketamine Clinic charges $565 per infusion ($3,390 for six). Bishop Health in Portland charges $800 per session. Ketamine-assisted psychotherapy packages run $2,295-$2,550. A standard initial series of 6 infusions runs $2400–$4800. Spravato (esketamine) may be partially or fully covered by insurance.
Mental Health Access
HRSA data (December 2025) shows Maine meets only 14.41% of mental health care needs in designated shortage areas, with 11 additional practitioners needed. Rural and northern counties face the most severe psychiatrist-to-population shortfalls. Maine has approximately 0.29 ketamine providers per 100,000 residents.
Frequently Asked Questions
- Yes. Ketamine is a Schedule III controlled substance that may be prescribed off-label by licensed physicians and qualified clinicians in Maine. Maine's joint controlled substance prescribing rules (Chapter 21) require electronic prescriptions, PMP checks, and documentation standards.
- MaineCare covers Spravato (esketamine) for eligible members with prior authorization. Coverage applies to adults 18+ with TRD who have failed at least two antidepressant trials. IV ketamine is not covered. Financial assistance programs and sliding-scale fees may be available at some Maine providers.
- Maine ketamine infusion prices range from $400 to $800 per session. Portland Ketamine Clinic charges $565 per infusion ($3,390 for six sessions). Ketamine-assisted psychotherapy packages range from $2,295 to $2,550 for multi-session protocols.