Ketamine Providers in Minnesota
9 providers across 8 cities
Minnesota has 9 ketamine therapy providers across 8 cities. The most common provider types are psychiatry practice, ketamine infusion clinic, pain management clinic. Providers in Minnesota commonly treat depression, anxiety, ptsd. Top cities include Maple Grove, Burnsville, Chanhassen, Edina, Golden Valley.
Ketamine Therapy in Minnesota
Minnesota offers a growing network of ketamine therapy clinics anchored by world-class research institutions including Mayo Clinic and the Minneapolis VA Medical Center. Ketamine is legally administered across the state for treatment-resistant depression, PTSD, anxiety, and chronic pain. While the Twin Cities area has the highest concentration of providers, telehealth evaluations are permitted under DEA-extended flexibilities, helping connect patients in rural Minnesota with qualified clinicians.
Minnesota ranks 26th nationally with 9 ketamine therapy providers, averaging 1.1 providers per city. The largest provider category is psychiatry practice (44.4% of providers). Maple Grove leads the state with 2 providers.
State Regulations
Minnesota regulates ketamine therapy through the Board of Medical Practice under Minnesota Statutes Chapter 152 (Schedule III). The Board has not adopted ketamine-specific clinical guidelines but enforces standard-of-care compliance. Nurse practitioners require a physician collaborative agreement under MN Stat. 148.235 to prescribe controlled substances. CRNAs may administer ketamine within their anesthesia scope.
Insurance & Medicaid Coverage
Minnesota Health Care Programs (MHCP), covering over 1.2 million enrollees, covers Spravato with prior authorization. Requirements include DSM-5 MDD diagnosis, failure of at least two antidepressants of different classes (6 weeks each), failure of augmentation therapy, psychotherapy trial, and prescription by or in consultation with a psychiatrist or PMHNP. Initial approval is 4 weeks; subsequent renewals 3 months.
Telehealth Options
Minnesota Statutes 62A.672 establishes strong telehealth parity requirements and permits initial psychiatric evaluations via telehealth. DEA telemedicine flexibilities extended through December 31, 2026 permit ketamine prescribing via telehealth without a prior in-person visit.
Cost of Ketamine Therapy
IV ketamine infusions in Minnesota typically cost $300–$700 per session. Twin Cities clinics range $450-$700 per infusion; some mission-driven clinics offer $300/session. Six-session bundles can be as low as $2,700. Rochester and Duluth clinics are generally slightly lower. A standard initial series of 6 infusions runs $2550–$4200. Spravato (esketamine) may be partially or fully covered by insurance.
Mental Health Access
Minnesota meets only 24.87% of mental health needs in designated shortage areas (HRSA, December 2025), requiring an estimated 114 additional practitioners. Most rural regions from the Arrowhead to southwest Minnesota carry geographic HPSA designations. Minnesota has approximately 0.18 ketamine providers per 100,000 residents.
Frequently Asked Questions
- Yes. Ketamine is a Schedule III controlled substance under Minnesota Statutes Chapter 152, and licensed physicians, psychiatrists, and appropriately supervised nurse practitioners may legally prescribe and administer it off-label. Clinics operate in Minneapolis, St. Paul, Rochester, Duluth, and surrounding suburbs.
- Minnesota Medicaid (MHCP) does not cover IV ketamine infusions. However, Spravato (esketamine nasal spray) is covered through the prior authorization process when patients meet strict clinical criteria, including failure of at least two antidepressants and prescription by a psychiatrist or PMHNP.
- IV ketamine infusions in Minnesota typically cost $300-$700 per session, with most Twin Cities clinics in the $450-$600 range. A standard induction series of six infusions runs approximately $2,700-$4,200. Some clinics offer package discounts.